Publications

Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer. Bauden M, Pamart D, Ansari D, Herzog M, Eccleston ME, Micallef J, Andersson B, Andersson R. Clin. Epigenetics, 2015;7:106. 

Effect of L-leucine graft content on aqueous solution behavior and membrane-lytic activity of a pH-responsive pseudopeptide. Chen R, Khormaee S, Eccleston ME, Slater NK. Biomacromolecules. 2009 Sep 14;10(9):2601-8. PMID: 19642668 

The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides. Chen R, Khormaee S, Eccleston ME, Slater NK. Biomaterials. 2009 Apr;30(10):1954-61. Epub 2009 Jan 12. PMID: 19138797

Synthesis and pH-responsive properties of pseudo-peptides containing hydrophobic amino acid grafts. Chen R, Eccleston ME, Yue Z, Slater NKH. J. Mater. Chem. 2009;19: 4217-4224.

The effect of high intensity focussed ultrasound (HIFU) on pH responsive PEGylated micelles. Smith MJ, Eccleston ME, Roberts ST, Webster DA and Slater NKH Proc. European Acoustics Association. 2008: 2293-2297

Aqueous solution behaviour and membrane disruptive activity of pH-responsive PEGylated pseudo-peptides and their intracellular distribution. Chen R, Yue Z, Eccleston ME, Slater NK. Biomaterials. 2008 Nov;29(32):4333-40. Epub 2008 Aug 15. PMID: 18708250

Fluorescence intensity and lifetime imaging of free and micellar-encapsulated doxorubicin in living cells. Dai X, Yue Z, Eccleston ME, Swartling J, Slater NK, Kaminski CF. Nanomedicine. 2008 Mar;4(1):49-56. Epub 2008 Jan 31. PMID: 18249155

A spectroscopic study of the self-association and inter-molecular aggregation behaviour of pH-responsive poly(l-lysine iso-phthalamide). Dai X, Eccleston ME, Yue Z, Slater NKH, Kaminski CF. Polymer. 2006;47: 2689-2698

Modulation of cell membrane disruption by pH-responsive pseudo-peptides through grafting with hydrophilic side chains. Chen R, Yue Z, Eccleston ME, Williams S, Slater NK. J Control Release. 2005 Nov 2;108(1):63-72. Epub 2005 Sep 2. PMID: 16139914

Modulation of the pH-responsive properties of poly(L-lysine iso-phthalamide) grafted with a poly(ethylene glycol) analogue. Yue Z, Eccleston ME, Slater NK. Biomaterials. 2005 Nov;26(32):6357-66. PMID: 15913772

Affinity capture of a biotinylated retrovirus on macroporous monolithic adsorbents: towards a rapid single-step purification process. Williams SL, Eccleston ME, Slater NK. Biotechnol Bioeng. 2005 Mar 30;89(7):783-7. PMID: 15643627

Design and in-vitro testing of effective poly (L-lysine iso-phthalamide) polymeric drug targeting systems for solid tumours. Eccleston, ME, Williams SL, Yue, Z, Chen, R., Lee, CK, Anikina, E, Pawlyn, C. Barrand, MA. and Slater, NKH. Trans IChemE, part C, Food and Bioproducts processing, 2005, 83, C2, 141-1466

PEGylation and aqueous solution behaviour of pH responsive poly (L-lysine iso-phthalamide). Yue, Z., Eccleston, ME. and Slater, NKH. Polymer. 2005; 46(8): 2497-2505

Bio-organic nanoprobes for tumour detection. Eccleston, ME., Lee, J,  Gilchrist, F, Slater, NKH. and Kaminski, CF. Optical Society of America (OSA) 9th Topical Meeting on Laser Applications to Chemical & Environmental Analysis. 2004; 9: FUF10. ISBN 1-55752-698-2, Annapolis, Maryland, USA

Optical characteristics of responsive biopolymers; co-polycondensation of tri-functional amino acids and Cy-3 bis-amine with diacylchlorides. Eccleston, M.E., Kaminski, C.F., Slater, N.K.H. and Briggs, M.S.J. Polymer. 2004;45(1): 25-32

pH-responsive pseudo-peptides for cell membrane disruption.  Eccleston, ME, Kuiper, M, Gilchrist, FM and Slater, NKH. Journal of Controlled Release. 2000;69(2): 297-307

Synthetic routes to responsive polymers; co-polycondensation of tri-functional amino acids with diacylchlorides. Eccleston, ME, Slater, NKH. and Tighe, BJ Reactive and Functional Polymers. 1999;42(2):  147-152